SHORT COMMUNICATION
Comparison of Incidence of Cardiovascular Risk
Factors and Selected Indices of Vascular
Endothelium Status in Women Aged 40-60
Jolanta Mieczkowska1, Jerzy Mosiewicz1, Tomasz Sodolski2, Wojciech Myśliński1
1Department of Internal Disease, Medical University of Lublin, Stanisława Staszica 16, 20-081 Lublin, Poland
2Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland
2Department of Cardiology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland
Pol. J. Environ. Stud. 2010;19(6):1391–1399
KEYWORDS
cardiovascular risk factorsC-reactive proteinmetalloproteinase-8-9tissue inhibitor ofmetalloproteinase-1tumor necrosis factorinsulingrowth-factor–binding-proteinadiponectinintercellularadhesive molecule-1sex hormone binding globulin
ABSTRACT
The aim of our study was to compare cardiovascular risk factors and selected indices of vascular
endothelium status in women aged 40-60, inhabiting urban (86 women) and rural (72 women) areas. In women
inhabiting rural regions compared with urban dwellers, a significantly lower incidence of metabolic syndrome
was found (31.7% vs. 66.7%) as well as higher waist circumference (92.65±13.56 vs. 86.25±13.56 cm), lower
values of rest heart rate (60.8±8.2/min. vs. 64.5±9.3/min.), less frequent occurrence of increased values of
diastolic blood pressure (14.8% vs. 24.4%), raised peptide C serum levels (48.5% vs. 57.1%), and higher IGF
BP1 serum values (7.94±6.84 vs. 6.97±8.41 ng/ml). Despite the differences in distribution of metabolic syndrome
and obesity in postmenopausal women inhabiting rural and urban areas in the Lublin region, there were
no significant differences in selected indices of vascular endothelial status.
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