Unpressurized Safekeeping of Transplant Organs Using the TOP-Liver® Storage Module
Grzegorz Śliwiński1, Aleksander Sieroń2, Rüdiger Poll1, Christine Thiele1, Zbigniew Śliwiński3
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1Institute of Biomedical Engineering, TU Dresden, Dresden, Germany
2Clinic of Internal Diseases and Physical Medicine, Silesian Medical University, Bytom, Poland
3Jan Kochanowski University of Humanities and Sciences, Kielce, Poland
Pol. J. Environ. Stud. 2010;19(4):861–864
The demand for transplant donor organs continues to grow worldwide as the level of medical care improves. This increased need is the primary driving force to develop new storage techniques for organ preservation. TOP-Liver® is an idea for a device for liver preservation conceived as a normothermic preservation system. Experimental work investigated the use of this system's storage module using cold preservation and analyzed it for use under standard preservation. Results show that organs stored in a cooling box must contact ice using standard storage methods; there is a correlation between the contact area and the median contact pressure. This experimental work demonstrates that established standard methods for organ storage can be significantly improved while serving as a starting point for future work and research concerning the relevance for transplant medicine.