Assessment of Work Environmental Hazard and Exposure of a Worker Utilizing 226Ra in an Oncological Center
Grzegorz Andryskowski1, Edward Kowalczyk2, Marta Michalska3, Marlena Broncel1
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1Department of Internal Diseases with the Unit of Clinical Pharmacology and Monitored Therapy,
Medical University in Łódź, Kniaziewicza 1-5, 91-347 Łódź, Poland
2Department of Human Physiology, Chair of Basic and Preclinical Sciences, Medical University in Łódź,
Hallera 1, 91-647 Łódź, Poland
3Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Medical University in Łódź,
Muszyńskiego 1, 90-151 Łódź, Poland
Pol. J. Environ. Stud. 2011;20(3):649–653
Our study presents dosimetric evaluation of activities associated with sealing in glass 72 sources of 226Ra prepared for utilization, and of the effect of an absorbed dose on a worker’s select laboratory parameters. During 3 h exposure to 226Ra of activity 31 GBq, it was demonstrated that taking the sources from a bunker in portions only for the time of sealing them in glass, decreases the worker’s exposure to the obtained dose from 91.5 mSv to 6 mSv, and additionally used 5 cm shield to 2 mSv. Nine days after the worker’s absorption of the radiation dose, we observed in laboratory tests disorders expressed by decreased numbers of white blood cells and neutrophils, decreased activity of antioxidative enzymes in erythrocytes, concentrations of protein thiol groups, vascular endothelial growth factors in serum, and an increase of plasma total antioxidant status level, of insulin-like growth factor I level, and urokinase-type plasminogen activator receptor level in blood serum.