In this study we used the somatic mutation and recombination test (SMART) in Drosophila melanogaster to evaluate the genotoxicity of ethyl methanesulfonate (EMS) and the effect of Rosa canina L. ethanol extract (RC_eta) on the genotoxicity of EMS. Application groups were prepared as Drosophila instant medium (DIM), including only 1ppm EMS and different concentrations (1, 2, and 4ppm) of RC_eta were added to DIM, including 1 ppm EMS. As a result of our study, statistically significant genotoxic effects of EMS (P<0.05) were removed by RC_eta. A particularly positive genotoxic effect of EMS has become inconclusive/ negative efficacy in both wing phenotypes on 2 and 4 ppm EMS+RC_eta application groups.