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ORIGINAL RESEARCH
GC/MS Analysis, Antimicrobial, Fungicidal
Activities and Toxicity of Rosmarinus
Officinalis Essential Oil Plant from Algeria
1
Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria
2
Laboratory of Biology, Water and Environment, 8 May 1945 University of Guelma, Algeria
3
Laboratory of applied chemistry and renewable energies, Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria
Submission date: 2024-01-02
Final revision date: 2024-02-10
Acceptance date: 2024-04-27
Online publication date: 2024-11-04
Publication date: 2025-01-28
Corresponding author
Hayette Bouabida
Water and Environment Laboratory, Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria., Algeria
Water and Environment Laboratory, Echahid Cheikh Larbi Tebessi University, Tebessa, Algeria., Algeria
Pol. J. Environ. Stud. 2025;34(3):2665-2672
KEYWORDS
TOPICS
ABSTRACT
Rosmarinus officinalis (family Lamiaceae), a spontaneous aromatic plant widespread in Algeria and
widely used in folk medicine, is also known as “Eklil”. Our work focuses on the study of the biological
activities of the essential oil of R. officinalis. Its chemical composition was studied by GC/MS. Twenty
one compounds were identified: The major compounds were: 1.8cineole (32.58%), Sabinene (15.92%),
and Camphene (14.41%). The results show that the essential oil of R. officinalis has strong antimicrobial
activity against strains tested, either bacterial (Klebsiella pneumoniae, Staphylococcus aureus, and
Streptococcus pneumoniae) or fungal (Penicillium expansum and Alternaria alternata). In addition, we
evaluated the toxicity induced by the essential oil of R. officinalis in a model of Drosophila melanogaster.
Exposure of adult flies to the essential oil via a fumigation method resulted in a mortality-concentration
relationship. The result of this study indicated that the values LC25, LC50, and LC90 of the EO of leaves
obtained after 24 h were 50.91, 81.32, and 207.42 μL/Lair, respectively. In light of our findings, attention
is drawn to the medicinal use of the plant. In addition, there is potential bio-insecticidal activity.
CONFLICT OF INTEREST
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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