Elimination of Amoxicillin from Hospital Wastewater Using the Cold Plasma Technique
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Institute of Environmental Industry, Ho Chi Minh City 700000, Vietnam
Department of Environmental Engineering, Dayeh University, Changhua 51591, Taiwan
Institute of Applied Technology, Thu Dau Mot University, Thu Dau Mot City, Binh Duong Province 750000, Vietnam
Institute of Applied Materials Science - VAST, Ho Chi Minh City 700000, Vietnam
Department of Science Management, Saigon University, Ho Chi Minh City 700000, Vietnam
Department of Environmental Sciences, Saigon University, Ho Chi Minh City 700000, Vietnam
Submission date: 2021-03-09
Final revision date: 2021-07-18
Acceptance date: 2021-08-17
Online publication date: 2021-12-30
Publication date: 2022-02-16
Corresponding author
Ha Manh Bui   

Environmental Sciences, Sai Gon University, 273 An Duong Vuong Street, 700000, Ho Chi Minh, Viet Nam
Pol. J. Environ. Stud. 2022;31(2):1237-1246
In this paper, a cold plasma process was employed for the removal of amoxicillin (AM) and total organic carbon (TOC) from real hospital wastewater in Vietnam via the statistical design of a central composite design (CCD), with three factors of initial pH, applied voltage, and reaction time, respectively. Under optimal treatment conditions of a reaction time of 36.5 min, initial pH of 10.5, and an applied voltage of 36.5 kV, a good TOC removal efficiency of ~72.4% as well as most of the amoxicillin was eliminated. In addition, theoretical approaches (e.g., DFT and NBO calculations) revealed the proposed major degradation pathways of AM and the final mineralization to H2O, CO2, SO4 2−, and NO3. The obtained results demonstrate the potential of employing a cold plasma process for the treatment of pharmaceutical-containing wastewater.
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