Low temperature and frost damage in winter pose a major threat to the production of passion fruit in Fujian Province. Determining the suitability regionalization of cultivation is important. This research combined the methods of historical disaster inversion, orchard positioning observations, and geographical displacement experiments to conduct the regionalization research. Fifty-two samples of passion fruit cold and freezing disasters were obtained, and mathematical statistical methods were used to establish frost damage grade indicators of the main varieties of passion fruit based on the daily extreme minimum temperature (Tmin). The frost damage grade index of Passion Fruit No. 1 and No. 3 was divided into four grades: mild, moderate, severe, and most severe. Verifying the disaster samples taken from the literature and the results of artificial climate chamber disaster experiments, the accuracy rate was 81.8%, so the grade index is of practical significance. According to the results of risk regionalization of cold and freezing injury of the main varieties of passion fruit, the regions with no or mild cold and freezing injury were mainly distributed in the coastal areas of Fujian Province, which is thus the region with the lowest risk of cold and freezing injury for planting passion fruit.