Vitality and Implication of Natural Products from Viburnum Grandiflorum: an Eco-Friendly Approach
Muhammad Suleman1, Shazia Nouren2, Syeda Mona Hassan3, Abul Hassan Faiz4, Ghulam Abbas Sahr5, Gul Afshan Soomro5, Muhammad Asif Tahir6, Munawar Iqbal7, Arif Nazir7
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1Department of Chemistry, Women University of Azad Jammu & Kashmir Bagh, Pakistan
2Department of Chemistry, Govt. College Women University, Sialkot, Pakistan
3Department of Chemistry, Lahore Garrison University, Lahore, Pakistan
4Department of Zoology, Women University of Azad Jammu & Kashmir Bagh, Pakistan
5Institute of Chemistry, Shah Abdul Latif University, Khairpur 66020, Sindh, Pakistan
6Department of Chemistry, University of Agriculture, Faisalabad, Pakistan
7Department of Chemistry, The University of Lahore, Lahore-Pakistan
Submission date: 2017-07-18
Final revision date: 2017-08-08
Acceptance date: 2017-09-03
Online publication date: 2018-02-20
Publication date: 2018-03-12
Pol. J. Environ. Stud. 2018;27(3):1407-1411
In this study we screened Viburnum grandiflorum for bioactive secondary metabolites and biological activity. Secondary metabolites were detected by phytochemical tests, and biological activity was confirmed through antimicrobial and anti-oxidant assays. Phytochemical screening (alkaloidal, tannins, terpenoids, flavonoids, anthraquinones, and glycosides) was performed with methanol, and aqueous and ethyl acetate extracts. Antibacterial activity against four bacterial strains — staphylococcus auries, Escherichia Coli, Bacillus subtillus, and salmonella typhi – were measured. Methanolic extract showed maximum inhibitory activity with diameter of zone of inhibition (11.66 mm), followed by n-hexane extract (9.33 mm) and then ethyl acetate extract. Four different fungi (Penicillium chrysogenum, Aspergillus flavus, Rhodotorula mucilaginosa, and Stachybotrys chartarum) were also tested against plant stem extract using different solvents. Dimethyl sulfoxide extract showed a maximum zone of inhibition at 20 mg/ml. Anti-oxidant activity of stem extract of Viburnum grandiflorum was evaluated by 1, 1-diphenyl- 2-picryl-hydrazyl (DPPH). Then we measured absorbance, and percentage activity at each concentration was found for three solvent extracts to get Ic50 values. These data support Viburnum grandiflorum as having enough potential to be used safely as an antimicrobial drug.
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