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ORIGINAL RESEARCH
Effect of Gamma Irradiation on Intestinal Crypts Survival in Mice Pretreated with N-Nitrosodiethylamine
I.P. Grudziński
Department of Food Studies and Nutrition Physiology, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Pol. J. Environ. Stud. 2000;9(4):281-283
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ABSTRACT
A new mathematical equation was developed by which whole-body exposure to gamma radiation may be used to predict the survival characteristic of the intestinal crypt in mice pretreated with N-nitrosodiethylamine (NDEA). A computer fitting procedure showed the best agreement between predicted and observed curves. The results suggest that less cells may survive in crypts after gamma irradiation of NDEA-treated mice.
CONFLICT OF INTEREST
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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| eISSN: | 2083-5906 |
| ISSN: | 1230-1485 |
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