About the Journal
In Memory of Professor Jerzy Radecki
Ownership and Management Statement
Editorial Office
Editorial Board
Scope
Impact Factor
Indexed by
Journal Impact Factor contributing items
Publication Frequency
Revenue Sources & Business Model
Contact
Subscription
Current issue
Online first
Instructions for Authors
Frequently Asked Questions
Editorial policies
Publication Policy Overview
Peer Review Policy
Research Ethics and Malpractice Policy
Plagiarism Policy
Conflict of Interest Policy
Open Access Policy
Instructions for Reviewers
Generative AI and AI-Assisted Technologies Policy
Advertising Policy
Direct Marketing & Manuscript Solicitation
Digital Archiving and Preservation Policy
CrossMark, Correction, and Retraction Policy
Archive
Editorial policies
Publication Policy Overview
Peer Review Policy
Research Ethics and Malpractice Policy
Plagiarism Policy
Conflict of Interest Policy
Open Access Policy
Instructions for Reviewers
Generative AI and AI-Assisted Technologies Policy
Advertising Policy
Direct Marketing & Manuscript Solicitation
Digital Archiving and Preservation Policy
CrossMark, Correction, and Retraction Policy
ORIGINAL RESEARCH
Effects of Fertilized Copper Sulfate on
the Przewalski’s Gazelles of Molybdenosis
in the Qinghai Lake Watershed
1
School of Life Science and Engineering, Southwest University of Science and Technology 621010, Mianyang, China
Submission date: 2024-04-17
Final revision date: 2024-06-24
Acceptance date: 2024-08-15
Online publication date: 2024-11-07
Publication date: 2025-08-20
Corresponding author
Xiaoyun Shen
Southwest University of Science and Technology, School of Life Science and Engineering, 59 Qinglong Road, 621010, Mianyang, China
Southwest University of Science and Technology, School of Life Science and Engineering, 59 Qinglong Road, 621010, Mianyang, China
Pol. J. Environ. Stud. 2025;34(5):6263-6269
KEYWORDS
TOPICS
ABSTRACT
This paper aimed to study the effect of copper sulfate fertilization (90 kg/hm2) on molybdenum
(Mo) poisoning of the Przewalski’s gazelle (P. przewalskii) in the Qinghai Lake basin. Soil, pasture,
and the Przewalski’s gazelle’s blood and hair samples were collected from the animal rescue center
in this study. The biochemical parameters of the Przewalski’s gazelle’s blood and the mineral contents
of the fodder and soil were ascertained. The findings demonstrated that the impacted pastures’ soil
and forage had considerably greater Mo levels (p < 0.01) than those of the healthy pastures. Compared
to the control group, the experimental gazelles had significantly lower Mo content in the blood and hair,
while the impacted gazelles had significantly higher copper and sulfur contents in the blood and hair
(p < 0.01). The levels of blood Hb, PCV, MCV, and MCH of the Przewalski’s gazelle in the fertilized
group had been extensively greater than those in the control group (p < 0.01). The tiers of blood
AST, LDH, CPK, and ALP of the Przewalski’s gazelle in the fertilized group had been extensively
greater than those in the control group. The contents of TP, ALB, and GLB in the fertilized group
had been substantially decreased than those in the control group. In comparison to the control group,
the fertilized group exhibited considerably higher activity of serum GSH-Px, SOD, T-AOC, and CAT
and a significantly lower MDA concentration. The results showed that the appropriate application
of copper sulfate could significantly increase the copper content in forage, regulate the molybdenumcopper
ratio in soil, and thus effectively improve the molybdenum toxicity symptoms of Przewalski’s
gazelle, improve the antioxidant ability of the gazelle, and alleviate the molybdenum toxicity condition.
CONFLICT OF INTEREST
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
REFERENCES (41)
1.
LIANG D., LI C. Habitat Suitability, Distribution Modelling and GAP Analysis of Przewalski's Gazelle Conservation. Animals, 14 (1), 2024. https://doi.org/10.3390/ani140....
2.
XIANG Z., YANG J., IKHUMHEN H.O., SHENG C., WONG L., REN X., ZHOU J., WANG W. Complete mitochondrial genome sequence of the Przewalski's gazelle (Procapra przewalskii). Conservation Genetics Resources, 11 (4), 369, 2019. https://doi.org/10.1007/s12686....
3.
YANG R. Current status of Przewalski's gazelle research. Journal of Animal Husbandry and Veterinary Medicine, 42 (06), 37, 2023.
4.
LIU T., JIANG Z., WANG W., WANG G., SONG X., XU A., LI C. Changes in habitat suitability and population size of the endangered Przewalski's gazelle. Global Ecology and Conservation, 43, 2023. https://doi.org/10.1016/j.gecc....
5.
PING W., PENG H., YONGCUNL L. From 300 to 3000, the "Plateau Elves" Witness the Ecological Changes in Gangcha. Qilian Mountain News, 2023.
6.
ZHANG J., JIANG F., CAI Z., DAI Y., LIU D., SONG P., HOU Y., GAO H., ZHANG T. Resistance-Based Connectivity Model to Construct Corridors of the Przewalski's Gazelle (Procapra Przewalskii) in Fragmented Landscape. Sustainability, 13 (4), 2021. https://doi.org/10.3390/su1304....
7.
REUSSER J.E., SIEGENTHALER M.B., WINKEL L.H.E., WACHTER D., KRETZSCHMAR R., MEULI R.G. Geochemical Soil Atlas of Switzerland - Distribution of Toxic Elements. Chimia, 77 (11), 758, 2023. https://doi.org/10.2533/chimia....
8.
XU L., ZHOU Z.F. Physiological Integration Affects Expansion of an Amphibious Clonal Plant from Terrestrial to Cu-Polluted Aquatic Environments. Scientific Reports, 7, 43931, 2017. https://doi.org/10.1038/srep43....
9.
LI Y., WANG Y., SHEN X., LIU F. The combinations of sulfur and molybdenum fertilizations improved antioxidant capacity of grazing Guizhou semi-fine wool sheep under copper and cadmium stress. Ecotoxicology and Environmental Safety, 222, 2021. https://doi.org/10.1016/j.ecoe....
10.
SHEN X., ZHAO K., MO B. Effects of Molybdenosis on Antioxidant Capacity in Endangered Przewalski's Gazelles in the Qinghai Lake National Nature Reserve in the Northwestern China. Biological Trace Element Research, 201 (8), 3804, 2023. https://doi.org/10.1007/s12011....
11.
XIAONA L., JINYUN W. Current status of molybdenum in soils in China. World Nonferrous Metals, (13), 248, 2019.
12.
KLIEM K.E., LEE A., RYMER C. The effect of stocking rate and supplementary selenium on the fatty acid composition and subsequent peroxidisability of poultry muscle tissues. Animal, 16 (3), 2022. https://doi.org/10.1016/j.anim....
13.
FENG J., CHEN J., XING C., HUANG A., ZHUANG Y., YANG F., ZHANG C., HU G., MAO Y., CAO H. Molybdenum Induces Mitochondrial Oxidative Damage in Kidney of Goats. Biological Trace Element Research, 197 (1), 167, 2020. https://doi.org/10.1007/s12011....
14.
BOROBIA M., VILLANUEVA-SAZ S., RUIZ DE ARCAUTE M., FERNANDEZ A., VERDE M.T., GONZALEZ J.M., NAVARRO T., BENITO A.A., ARNAL J.L., DE LAS HERAS M., ORTIN A. Copper Poisoning, a Deadly Hazard for Sheep. Animals, 12 (18), 2022. https://doi.org/10.3390/ani121....
15.
CUI S.-G., ZHANG Y.-L., GUO H.-W., ZHOU B.-H., TIAN E.-J., ZHAO J., LIN L., WANG H.-W. Molybdenum-Induced Apoptosis of Splenocytes and Thymocytes and Changes of Peripheral Blood in Sheep. Biological Trace Element Research, 201 (9), 4389, 2023. https://doi.org/10.1007/s12011....
16.
ARTHINGTON J.D., RECHCIGL J.E., YOST G.P., MCDOWELL L.R., FANNING M.D. Effect of ammonium sulfate fertilization on bahiagrass quality and copper metabolism in grazing beef cattle. Journal of Animal Science, 80 (10), 2002. https://doi.org/10.2527/2002.8....
17.
ZHAI B., ZHAO K., LIU F., SHEN X. Studies of High Molybdenum-Induced Copper Deprivation in P. przewalskii on The Qinghai Lake Pasture in China. Applied Sciences, 11 (11), 2021. https://doi.org/10.3390/app111....
18.
CLARKSON A.H., KENDALL N.R. UK ruminant farmer understanding of copper-related terminology. Preventive Veterinary Medicine, 205, 2022. https://doi.org/10.1016/j.prev....
19.
MONYA Z., YUJUN M., TING X. Characterization of the spatial distribution of soil moisture during the growing season in Qinghai Lake Basin. Water Resources and Hydropower Technology (in Chinese and English), 54 (03), 85, 2023.
20.
HUO B., WU T., SONG C., SHEN X. Effects of Selenium Deficiency in the Environment on Antioxidant Systems of Wumen Semi-Fine Wool Sheep. Polish Journal of Environmental Studies, 29 (2), 1649, 2020. https://doi.org/10.15244/pjoes....
21.
QI X.-E., WANG C., HE T., DING F., ZHANG X., AN L., XU S. Bacterial community changes and their responses to nitrogen addition among different alpine grassland types at the eastern edge of Qinghai-Tibetan Plateau. Archives of Microbiology, 203 (10), 5963, 2021. https://doi.org/10.1007/s00203....
22.
HOU W. Research on Ecological and Environmental Geological Conditions and Ecological and Environmental Geological Problems in Qinghai Lake Basin, 2020.
23.
FOTEVA V., FISHER J.J., QIAO Y., SMITH R. Does the Micronutrient Molybdenum Have a Role in Gestational Complications and Placental Health? Nutrients, 15 (15), 2023. https://doi.org/10.3390/nu1515....
24.
SONG C., GAN S., SHEN X. Effects of Nano-Copper Poisoning on Immune and Antioxidant Function in the Wumeng Semi-Fine Wool Sheep. Biological Trace Element Research, 198 (2), 515, 2020. https://doi.org/10.1007/s12011....
25.
ZHAI B., ZHAO K., SHEN X. Effects of Sulphur Fertilizer on Copper Metabolism in Grazing Tibetan Sheep in Fertilized Pasture. Polish Journal of Environmental Studies, 30 (6), 5351, 2021. https://doi.org/10.15244/pjoes....
26.
CLARKSON A.H., PAINE S.W., KENDALL N.R. Evaluation of the solubility of a range of copper sources and the effects of iron & sulphur on copper solubility under rumen simulated conditions. Journal of Trace Elements in Medicine and Biology, 68, 2021. https://doi.org/10.1016/j.jtem....
27.
MIN X., YANG Q., ZHOU P. Effects of Nano-copper Oxide on Antioxidant Function of Copper-Deficient Kazakh Sheep. Biological Trace Element Research, 200 (8), 3630, 2022. https://doi.org/10.1007/s12011....
28.
HELMER C., HANNEMANN R., HUMANN-ZIEHANK E., KLEINSCHMIDT S., KOELLN M., KAMPHUES J., GANTER M. A Case of Concurrent Molybdenosis, Secondary Copper, Cobalt and Selenium Deficiency in a Small Sheep Herd in Northern Germany. Animals (Basel), 11 (7), 2021. https://doi.org/10.3390/ani110....
29.
LI Y., SHEN X., LIU F., LUO L., WANG Y. Molybdenum Fertilization Improved Antioxidant Capacity of Grazing Nanjiang Brown Goat on Copper-Contaminated Pasture. Biological Trace Element Research, 200 (3), 1156, 2022. https://doi.org/10.1007/s12011....
30.
THORNDYKE M.P., GUIMARAES O., TILLQUIST N.M., ZERVOUDAKIS J.T., ENGLE T.E. Molybdenum Exposure in Drinking Water Vs Feed Impacts Apparent Absorption of Copper Differently in Beef Cattle Consuming a High-Forage Diet. Biological Trace Element Research, 199 (8), 2913, 2021. https://doi.org/10.1007/s12011....
31.
BAMPIDIS V., AZIMONTI G., BASTOS M.L., CHRISTENSEN H., DUSEMUND B., KOUBA M., DURJAVA M.K., LÓPEZ-ALONSO M., PUENTE S.L., MARCON F., MAYO B., PECHOVÁ A., PETKOVA M., RAMOS F., SANZ Y., VILLA R.E., WOUTERSEN R., FLACHOWSKY G., GROPP J., CUBADDA F., LÓPEZ-GÁLVEVEZ G., MANTOVANI A. Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V. EFSA Journal, 17 (2), e05606, 2019. https://doi.org/10.2903/j.efsa....
32.
TARNACKA B., JOPOWICZ A., MAŚLIŃSKA M. Copper, Iron, and Manganese Toxicity in Neuropsychiatric Conditions. International Journal of Molecular Sciences, 22 (15), 2021. https://doi.org/10.3390/ijms22....
33.
SHEN X., HUO B., LI Y., SONG C., WU T., HE J. Response of the critically endangered Przewalski's gazelle (Procapra przewalskii) to selenium deprived environment. Journal of Proteomics, 241, 2021. https://doi.org/10.1016/j.jpro....
34.
CLARKSON A.H. The Copper Conundrum: Elucidating the Modes of Copper Antagonism in the Rumen, 2020.
35.
THORNDYKE M.P., GUIMARAES O., MEDRADO M., LOH H.Y., TANGREDI B.V., REYES A., BARRINGTON R.K., SCHMIDT K., TILLQUIST N.M., LI L., IPPOLITO J.A., ZERVOUDAKIS J.T., WAGNER J.J., ENGLE T.E. The Effects of Long-term Molybdenum Exposure in Drinking Water on Molybdenum Metabolism and Production Performance of Beef Cattle Consuming a High Forage Diet. Biological Trace Element Research, 201 (9), 4360, 2023. https://doi.org/10.1007/s12011....
36.
JOMOVA K., ALOMAR S.Y., ALWASEL S.H., NEPOVIMOVA E., KUCA K., VALKO M. Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants. Archives of Toxicology, 98, 1323, 2024. https://doi.org/10.1007/s00204....
37.
HU Z., NIE G., LUO J., HU R., LI G., HU G., ZHANG C. Molybdenum and Cadmium Co-induce Pyroptosis via Inhibiting Nrf2-Mediated Antioxidant Defense Response in the Brain of Ducks. Biological Trace Element Research, 201 (2), 874, 2023. https://doi.org/10.1007/s12011....
38.
WU X., CAO W., JIA G., ZHAO H., CHEN X., WU C., TANG J., WANG J., LIU G. New insights into the role of spermine in enhancing the antioxidant capacity of rat spleen and liver under oxidative stress. Animal Nutrition, 3 (1), 85, 2017. https://doi.org/10.1016/j.anin....
39.
HUO B., HE J., SHEN X. Effects of Selenium-Deprived Habitat on the Immune Index and Antioxidant Capacity of Przewalski's Gazelle. Biological Trace Element Research, 198 (1), 149, 2020. https://doi.org/10.1007/s12011....
40.
GHEISARI H.R., MOTAMEDI H. Chloride salt type/ionic strength and refrigeration effects on antioxidant enzymes and lipid oxidation in cattle, camel and chicken meat. Meat Science, 86 (2), 377, 2010. https://doi.org/10.1016/j.meat....
41.
WANG W., ZHANG Z., LIU X., CAO X., WANG L., DING Y., ZHOU X. An Improved GC-MS Method for Malondialdehyde (MDA) Detection: Avoiding the Effects of Nitrite in Foods. Foods, 11 (9), 2022. https://doi.org/10.3390/foods1....
Share
RELATED ARTICLE
| eISSN: | 2083-5906 |
| ISSN: | 1230-1485 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
