In order to strengthen the removal efficiency of heterocyclic nitrogenous compounds in industrial wastewater, a new bacterial strain identified as Bacillus sp. LH-1 was isolated, which could use quinoline as its sole carbon, nitrogen and energy source. The inducing conditions and kinetic properties of quinoline biodegradation by the strain were explored. The results showed that the strain Bacillus sp. LH-1 exhibited maximum tolerance of 700 mgL^-1quinoline concentration. After the strain was activated under the conditions of 200 mgL^-1 quinoline for 120 h, the quinoline degradation was triggered, and the quinoline degradation rate increased approximately 10 times, from 2.030mg (L•h)^-1 to 21.508 mg (L•h)^-1. When the initial concentration of quinoline was 300 mgL^-1, more than 97% quinoline degradation occured within 12 h at pH 7 and at a temperature of 37ºC. The degradation kinetics of quinoline by strain Bacillus sp. LH-1 followed Haldane’s model and indicated that the strain isolated in this study could be used for degradation of heterocyclic nitrogenous compounds in industrial wastewater.