A theoretical model of regional Sci-Tech innovation-driven strategic emerging industry development is constructed with the modern service industry as the mediating variable and regional marketization level as the moderating variable. Based on Chinese provincial panel data from 2010- 2020, a multiple regression model is used to empirically analyze the mechanism of the role of regional Sci-Tech innovation driving the development of the strategic emerging industry. The research results show that: regional Sci-Tech innovation significantly drives the development of the strategic emerging industry; the modern service industry plays a partly intermediary role in the process of regional Sci- Tech innovation driving the growth of the strategic emerging industry; the level of marketization plays a positive moderating role in the relationship between regional Sci-Tech innovation and modern service industry development, and modern service industry and strategic emerging industry development; the level of marketization has a positive effect on the relationship between regional Sci-Tech innovation and The marketization level plays a positive regulating role in the relationship between regional Sci-Tech innovation and the development of modern service industry and the development of modern service industry and strategic new industry.