The hilly region of the Sichuan basin has unique natural topography, geomorphology, geology, and hydrology, with intensive human activities in the area. Therefore, it is of great significance to carry out research on heavy metal characteristics. In this study, taking five villages of Zigong city as a sample, the content of eight kinds of heavy metals in soil was determined (Cu, Cd, As, Pb, Cr, Zc, Ni, and Hg) based on ordinary Kriging. The results showed that Cd, Pb, Ni, and Zn content in the research area was higher than the background value and had a good concentration with all of the heavy metal contents lying within the national standards. Through soil parent material, soil environment, atmospheric environment, and water environment analysis of heavy metals, it was found that higher levels of heavy metals in the research area were mainly affected by agricultural and industrial activities (atmospheric dustfall). This was generally where there were intense areas of human activity – especially in and around transport routes and construction areas. It was also found that the soybean crop exhibited a strong Cd accumulation ability. This soybean planting should be reduced to control the distribution of Cd. Zn and Cu had a positive enrichment effect on rice, soybeans, and other crops, and had little enrichment effect on grapefruit. This study showed the effect human activities have on the quality of soil quality on the crop. This research has great significance for the ecologically sustainable development of society.