ORIGINAL RESEARCH
Association between Consumer Practices
and Phthalate Exposure in Children and their
Parents from Slovakia
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Department of Zoology and Anthropology, Faculty of Natural Sciences,
Constantine the Philosopher University in Nitra, Slovak Republic
Submission date: 2018-01-09
Final revision date: 2018-02-22
Acceptance date: 2018-02-28
Online publication date: 2018-11-16
Publication date: 2019-01-28
Corresponding author
Henrieta Hlisníková
Department of Zoology and Anthropology, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra, Slovak Republic, Tr. A. Hlinku 1, 94974 Nitra, Slovak Republic
Pol. J. Environ. Stud. 2019;28(3):1195-1202
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ABSTRACT
Phthalates represent endocrine disrupting chemicals, with harmful effect on the hormonal balance
of the human body. Food is a substantial source of exposure to phthalates. The aim of study was to
investigate association between phthalate exposure of children and their parents from Slovakia (children
n = 51, parents n = 27) and their consumer practices. We analysed urine samples by high performance
liquid chromatography and tandem mass spectrometry (HPLC-MS/MS) to determine concentrations
of phthalate metabolites monoethyl phthalate (MEP), monomethyl phthalate (MMP), mono-n-buthyl
phthalate (MnBP), mono-iso-buthyl phthalate (MiBP), monocyclo-hexyl phthalate (MCHP), mono(2-
ethylhexyl) phthalate (MEHP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethyl-
5-oxohexyl) phthalate (MEOHP), mono(2-ethyl-5-carboxypentyl) phthalate (MECPP) and mono(2-
carboxymethylhexyl) phthalate (McMHP), mono-n-octyl phthalate (MnOP) and mono-isononyl
phthalate (MiNP). We observed significantly higher concentrations of di (2-ethylhexyl) phthalate
(DEHP) metabolites and MiBP in children in comparison with parents (p≤0.05). We found statistically
significant association between concentrations of some phthalates and consumption of food packed in
the plastic containers, drinking of milk and strongest association was detected between consumption of
sliced salami in a plastic package and concentrations of all DEHP metabolites (p≤0.05). We concluded
that consumption of the fat rich food stored in the plastic containers together with socioeconomic status
and age could affect urinary concentration of phthalate metabolites.
CONFLICT OF INTEREST
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
CITATIONS (3):
1.
Phthalates Exposure and Occupational Symptoms among Slovakian Hairdressing Apprentices
Branislav Kolena, Ida Petrovicova, Miroslava Sidlovska, Henrieta Hlisnikova, Eliska Tomasovova, Veronika Zoldakova, Hana Trajtelova, Lubomir Rybansky, Sona Wimmerova, Tomas Trnovec
Applied Sciences
2.
Non-dietary exposure to phthalates in primary school children: Risk and correlation with anthropometric indices, cardiovascular and respiratory diseases
Yuchen Wang, Lixin Wang, Zhiyu Jiang, Meinan Qu, Ziyan Meng, Qinghua Sun, Yanjun Du, Yanwen Wang
Ecotoxicology and Environmental Safety
3.
Web-based behavioral intervention to reduce exposure to phthalate metabolites, bisphenol A, triclosan, and parabens in mothers with young children: A randomized controlled trial
Ju Hee Kim, Jung Min Kwak, Hyunjin Kang
International Journal of Hygiene and Environmental Health