This study collected waste rock samples during antimony mining and then probed into the releasing characteristics and regularities of heavy metals Sb and As under different factors (solid-to-liquid ratio, particle size, temperature, agitation intensity, pH value of leaching solution and leaching intensity) through indoor static soaking and dynamic leaching experiment. The results showed that: the smaller solid-to-liquid ratio, smaller particle size, or higher soaking liquid temperature could achieve the faster dissolution and precipitation rate of heavy metals; agitation could accelerate the dissolution and precipitation of heavy metals; the lower pH value could help to obtain more heavy metals deposited; the higher leaching intensity could make the rate of heavy metal reach the precipitation peak faster. Meanwhile, an equation fitting was conducted to the changing situation of Sb and As precipitation amount from antimony waste rocks with different influence factors under static and dynamic leaching, and the fitting results were good. This study was to reveal the releasing characteristics of heavy metal Sb and As in antimony mining waste rocks, so as to promote the harmonious development of metal mines.