The present investigation undertakes a comprehensive techno-economic analysis to assess the viability of producing malic acid sustainably from crude glycerol, obtained as a byproduct of biodiesel refining, at an industrial scale of 100 MT/day, utilizing simulation models developed from earlier studies. In this process, 4.1 MT of malic acid and 0.45 MT of bioethanol were produced per day. The high-value malic acid production plant is projected to require a total capital investment of $20.46 M, accompanied by annual operating expenses of $45.46 M. The annual revenue is estimated at $61.60 M, with key economic indicators including an internal rate of return (IRR) of 10.93%, a payback period of 6.71 years, a return on investment (ROI) of 14.90%, and a net present value (NPV) of $11.90 M. The minimum selling price (MSP) of malic acid is $3.6/kg, with the minimized achievable margin of the MSP at $2.9/kg at 30% solid loading, demonstrating the process’s economic viability and potential for low-cost malic acid production.