High natural heavy metal levels in Southwest China’s soils often lead to farmland contamination, and developing cost-effective risk mitigation strategies is crucial for safe agricultural production. This study evaluated profile reconstruction of a copper (Cu)- and cadmium (Cd)-contaminated vegetable production base in Kunming via deep soil mixing. Soil profile analysis revealed a clear surface accumulation of Cd and available Cu/Cd in the topsoil. Deep plowing to a depth of 50 cm effectively reduced the available Cu and Cd concentrations in the newly formed topsoil from 5.60±1.81 mg kg⁻¹ to 2.09±1.77 mg kg⁻¹ (a 63% reduction) and from 0.143±0.064 mg kg⁻¹ to 0.032±0.035 mg kg⁻¹ (a 78% reduction), respectively. The intervention reduced the mean total Cd concentration to 0.22±0.11 mg kg⁻¹, alongside a drop in the Cd exceedance rate from 80% to 20%. Soil pH and phosphorus/potassium contents remained stable; however, levels of soil organic matter and available nitrogen declined significantly. Field experiments confirmed that deep plowing effectively reduced the Cu and Cd contents in the edible parts of vegetables. Therefore, deep tillage presents a practical and rapid strategy for mildly contaminated sites with vertical metal accumulation, allowing for simultaneous production and remediation.