ORIGINAL RESEARCH
Synthesis of Silver Nanoparticle from Allium
sativum as an Eco-Benign Agent
for Biological Applications
| 1 | Department of Basic Sciences, University of Veterinary and Animal Sciences, Lahore (Jhang-Campus), Pakistan |
| 2 | Deputy Director, Livestock and Dairy Development Department, Punjab, Tehsil Shorkot, District Jhang, Pakistan |
| 3 | Department of Pathobiology, University of Veterinary and Animal Sciences, Lahore, (Jhang-Campus), Pakistan |
| 4 | Department of Biochemistry, University of Agriculture, Faisalabad, Pakistan |
| 5 | Department of Environmental Sciences, COMSATS University Islamabad, Vehari Campus, Punjab, Pakistan |
| 6 | Department of Biology, College of Sciences, Princess Nourah bint Abdulrahman University (PNU),
Riyadh 11671, Saudi Arabia |
| 7 | Department of Chemistry, The University of Lahore, Lahore, Pakistan |
CORRESPONDING AUTHOR
Submission date: 2020-12-14
Final revision date: 2021-04-08
Acceptance date: 2021-04-13
Online publication date: 2021-12-22
Publication date: 2022-01-28
Pol. J. Environ. Stud. 2022;31(1):533–538
KEYWORDS
TOPICS
ABSTRACT
The study focuses on the fabrication of silver nanoparticles (Ag NPs) using aqueous extracts
of Allium sativum as reducing agents. Silver ion becomes a good carrier of bioactive compounds of
Allium sativum, so their biochemical potential such as total phenolic and flavonoids were evaluated.
Results showed that as a concentration increases TPC and TFC were also increased. Similar to their
secondary metabolite, scavenging potential of Ag NPs of Allium sativum was also monitored. Green
synthesized Ag NPs exhibited significant antibacterial activity 24±2.6, 22±1.4, 19±2.7 and 20±3.17
against B. subtilis, S. aureus, E. coli and P. multocida bacterial strains respectively. Moreover, Ag NPs
of garlic did not show any mutagenicity against mutant strain of S. typhimurium TA98 & TA100. Brine
shrimp lethality assay (BSLA) showed their dose dependent effect. Finally, green synthesized Ag NPs
of garlic presented anti-proliferative effect against HEPG2 cell line.
RELATED ARTICLE
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.